Rat Model Data on 2-Methoxyestradiol Effects After Subarachnoid Hemorrhage

A 45.9 KB Excel dataset from a retracted study by Qiang Hu, last updated in 2026. It contains experimental results investigating the effects of 2-Methoxyestradiol on neuroinflammation and brain edema in a rat model of subarachnoid hemorrhage. Measurements include neurological scores, brain water content, blood-brain barrier permeability, and levels of inflammatory biomarkers.

Use Cases

• Analyze correlations between neurological scores and biomarker levels based on the described experimental measurements.
• Model the relationship between brain water content and inflammatory factors like IL-1β, IL-6, and TNF ɑ based on the study's findings.
• Investigate the effects of a pharmacological treatment on tight junction protein expression (ZO-1, occludin) based on the described western blotting results.

Strengths

• Data is openly licensed under CC-BY-4.0.
• The experimental protocol and measured outcomes are described in detail in the provided abstract.

Limitations

• Row count and column definitions are unknown, requiring manual inspection after download.
• The dataset is very small at 45.9 KB, indicating limited scope.
• The associated research paper is marked as retracted, which may affect data interpretation.

Provenance

Source

figshare, author Qiang Hu.

Collection Method

Data generated from a laboratory rat model of subarachnoid hemorrhage, with measurements taken via neurological scoring, ELISA, western blotting, and other assays.

Time Range

Measurements taken at 24 hours after surgery induction.

Freshness

Last updated 2026-04-27 13:30:29; freshness should be verified.

Geography

Laboratory study; geographic location is unknown.