Serum Progesterone Levels and Outcomes in 917 Frozen Embryo Transfer Cycles

917 hormone replacement frozen embryo transfer cycles from a single-center retrospective cohort study conducted between 2017 and 2023. The data, shared by Goksu Goc, explores the association between pre-transfer progesterone levels and live birth rates under a specific rescue protocol. Results indicate a live birth rate of 19.2% for cycles with pre-transfer progesterone below 5 ng/mL, compared to 43.8% for levels between 5–7.49 ng/mL.

Use Cases

• Predicting live birth outcomes based on pre-transfer progesterone levels and rescue intervention status.
• Analyzing miscarriage risk among clinical pregnancies stratified by progesterone thresholds.
• Building models to identify poor-prognosis subgroups in frozen embryo transfer cycles.
• Calibrating assay-specific signals for progesterone measurement across different clinical platforms.

Strengths

• Data covers 917 clinical cycles, providing a substantial sample for analysis.
• Includes detailed stratification of 267 rescue cycles by pre-transfer progesterone levels (<5, 5–7.49, 7.5–9.99 ng/mL).
• Study period spans six years (2017–2023), offering longitudinal clinical context.
• Analyses include multivariable logistic regression and bootstrap resampling for robustness.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for specific modeling tasks.
• The study design is retrospective and single-center, which may limit generalizability.

Provenance

Source

Single-center retrospective cohort study.

Collection Method

Clinical data collected under an institutional protocol, with progesterone measured by Cobas® e411 ECLIA.

Time Range

2017–2023

Freshness

Last updated 2026-06-01 04:17:41; freshness should be verified.