XNX Tablets: Multi-Target Pharmacology Study in Hypoxic Mouse Model

Zhihui Wang published a research paper on figshare in 2026 detailing a study on Xinnaoxin (XNX) tablets. The study investigates the mechanisms by which XNX ameliorates high-altitude polycythemia-associated cardiac injury in a hypobaric hypoxia mouse model. The dataset is a 119.8 KB PDF containing the full research article.

Use Cases

• Analyze the effects of a traditional medicine on blood parameters and hemorheology based on the described experimental results.
• Study the modulation of NF-κB, MAPK, and PI3K/AKT signaling pathways in a cardiac injury model based on the described Western blot analyses.
• Investigate the relationship between hypobaric hypoxia, ineffective erythropoiesis, and cardiac oxidative stress based on the described multi-level assessments.

Strengths

• The dataset is published under a CC-BY-4.0 license, permitting broad reuse.
• The description provides a detailed methodological breakdown of the in-vivo study, including specific biomarkers and pathways analyzed.

Limitations

• The dataset is a single 119.8 KB PDF document; the underlying raw experimental data (e.g., numerical measurements) is not provided in a machine-readable format.
• Column-level documentation is absent; field semantics must be inferred from the research article.
• Row count is unknown, which may limit suitability assessment for computational analysis.

Provenance

Source

Zhihui Wang via figshare.

Collection Method

Data appears to be generated from a laboratory study using a hypobaric hypoxia mouse model, with analyses including UPLC-Q-TOF-MS, blood tests, histopathology, echocardiography, and Western blot.

Freshness

Last updated 2026-05-28 04:53:03; freshness should be verified.