Epimedium Effects on Alzheimer's Disease in a Rat Model

A dataset from a study investigating the effects of the herb Epimedium on Alzheimer's disease in a rat model. The data likely contains results from cognitive tests, histopathology, and molecular assays measuring cytokine levels and gene expression. The dataset was authored by Jie Gao and last updated on April 20, 2026.

Use Cases

• Analyze the relationship between KAT2B expression and cognitive deficits based on the described experimental results.
• Model the effects of herbal intervention on neuroinflammatory markers like IL-1β and TNF-α based on the described ELISA and qRT-PCR data.
• Investigate the correlation between histopathological damage in hippocampal neurons and behavioral test scores based on the described Morris water maze and H&E staining results.

Strengths

• Data is derived from a controlled in vivo study with a described AD model and control group.
• The study measured multiple endpoints, including cognitive function, histopathology, and molecular targets like KAT2B and NF-κB.
• Dataset is openly available under a CC-BY-4.0 license.

Limitations

• Row count and column-level documentation are unknown, which limits suitability assessment.
• The dataset is very small at 12.4 KB, suggesting limited scope or summary-level data.
• Data freshness should be verified as the last update date is in the future (2026-04 20).

Provenance

Source

figshare

Collection Method

Generated from a laboratory study involving an AlCl3 and D-galactose-induced AD rat model, with assessments via Morris water maze, H&E staining, ELISA, and qRT-PCR.

Time Range

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Freshness

Last updated 2026-04-20 04:12:07

Geography

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