N-acyl-homoserine Lactone Quorum Sensing Data from Actinomycetota and Pseudomonadota

44.1 KB of data from a study investigating N-acyl-homoserine lactone-based quorum sensing in underexplored bacterial lineages. The dataset, authored by Christy R. Handel and last updated in April 2026, likely contains results from genomic analyses, hidden Markov model searches, and liquid chromatography-mass spectrometry assays on four bacterial strains from Hawai'i and the Bahamas. It expands the known diversity of bacterial signaling systems beyond the canonical Pseudomonadota model.

Use Cases

• Comparative genomic analysis of luxI/R homologs based on the described phylogenetic and domain architecture findings.
• Modeling non-canonical quorum sensing regulatory frameworks based on the described solitary luxI genes and associated metabolic genes.
• Training classifiers to identify AHL-QS systems in underexplored microbial lineages based on the described hidden Markov model (HMM) approach.

Strengths

• Data is derived from a targeted study on four specific bacterial strains, including two newly described species.
• Analysis methods are detailed, including custom HMMs, LC-MRM-MS, and targeted gene disruption.
• Licensed under CC-BY-4.0 for open reuse.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• The dataset is very small (44.1 KB), indicating a limited scope focused on a specific research question.
• Description metadata is limited; actual data structure and quality require manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely contains results from genomic context analysis, protein phylogeny, LuxR domain architecture study, and liquid chromatography-multiple reaction monitoring-mass spectrometry (LC-MRM-MS).

Time Range

null

Freshness

Last updated 2026-04-20 05:20:48; freshness should be verified.

Geography

Includes bacterial strains from Hawai'i (taro lo‘i, lava cave) and San Salvador Island, Bahamas (hypersaline mat).