Data Sheet 5: Xinnaoxin Tablet Study on High-Altitude Cardiac Injury

Zhihui Wang published a research data sheet on figshare in May 2026. The 2.7 MB PDF likely contains experimental results from a study investigating Xinnaoxin tablets' effects on high-altitude polycythemia-associated cardiac injury in a mouse model. The description details assessments of blood parameters, hemorheology, bone marrow cells, serum cytokines, cardiac histopathology, echocardiography, oxidative stress indicators, and Western blot analyses.

Use Cases

• Analyze the relationship between hypobaric hypoxia and cardiac injury based on echocardiography and histopathology data mentioned in the description.
• Investigate the modulation of signaling pathways like NF-κB and MAPK based on Western blot phosphorylation status data mentioned in the description.
• Study the effects of a herbal formulation on erythropoiesis based on bone marrow CD71+ cell proportion and serum EPO level data mentioned in the description.
• Evaluate oxidative stress and antioxidant response in cardiac tissue based on MDA, T-AOC, CAT, and SOD indicator data mentioned in the description.
• Correlate inflammatory cytokine levels with cardiac injury based on serum TNF-α, IL-1β, and IL-6 data mentioned in the description.

Strengths

• The description provides a detailed methodological breakdown of multi-level analyses, including blood tests, imaging, and molecular assays.
• The dataset is openly available under a CC-BY-4.0 license.
• The file size is 2.7 MB, indicating a contained document.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The data is presented in a PDF format, which may require extraction for computational analysis.

Provenance

Source

figshare

Collection Method

Experimental data from a hypobaric hypoxia mouse model study using UPLC-Q-TOF-MS, blood analysis, echocardiography, histopathology, and Western blot.

Freshness

Last updated 2026-05-28 04:53:03; freshness should be verified.