CLL Cell-Derived Soluble Factors and Normal B Cell Functionality

Michelle Maria Elbert published a dataset on figshare in May 2026 investigating the influence of chronic lymphocytic leukemia cell-derived soluble factors on normal B cells. The data likely contains results from functional B-cell assays measuring plasma cell differentiation, proliferation, cell death, and activation markers CD80, CD86, and CD25. The dataset is 172.6 KB and is shared under a CC-BY-4.0 license.

Use Cases

• Analyzing B-cell activation levels based on CD80, CD86, and CD25 marker data mentioned in the description
• Comparing plasma cell differentiation rates between CLL patient serum and control serum conditions
• Investigating correlations between B-cell proliferation and cell death in in vitro co-culture experiments

Strengths

• Dataset is licensed as CC-BY-4.0, allowing for broad reuse.
• The description provides a clear methodological context for the likely data, including specific assay types and measured markers.

Limitations

• The dataset is very small at 172.6 KB, indicating a limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Functional B-cell assays performed in vitro, as described.

Freshness

Last updated 2026-05-15 05:52:09; freshness should be verified.