FGF-Based Biomarker Protocol for Cardiovascular Risk in CKD

55.7 KB of data and R code for deriving a composite biomarker score from multiple quantitative variables. The protocol, authored by Manuel Martí Antonio and last updated in April 2026, describes a method to combine biomarkers into a score for classifying individuals. This score can be used to evaluate associations with CKD stage and cardiovascular event-free survival.

Use Cases

• Deriving a composite biomarker score based on multiple quantitative variables.
• Classifying patient groups with similar biomarker profiles for risk stratification.
• Evaluating the association of a composite score with disease stage, as mentioned for CKD.
• Assessing the relationship between derived biomarker groups and clinical outcomes like event-free survival.

Strengths

• Includes R code for reproducible analysis of the described protocol.
• Released under a permissive CC-BY-4.0 license, allowing for broad reuse and modification.
• The protocol is specifically designed for downstream survival and disease stage analysis.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 55.7 KB size suggests a very limited scope, likely containing code and a small example dataset.

Provenance

Source

figshare

Collection Method

The protocol describes a methodological approach for data integration and score derivation.

Freshness

Last updated 2026-04-20 08:55:11; freshness should be verified.