Rat Kidney Effects of Nonylphenol and Crocin Treatment

Experimental data from a study on the late-stage renal effects of nonylphenol exposure and the potential nephroprotective role of crocin in Wistar rats. The dataset includes body and kidney weights, histopathological scores, glomerular morphometry, and biochemical markers for renal function and oxidative stress. It was authored by Esra Babaoğlu and last updated on 2026-06-02.

Use Cases

• Modeling dose-response relationships for nephrotoxicity based on biochemical parameters like BUN and creatinine.
• Analyzing correlations between oxidative stress markers (SOD, GPx, MDA) and histopathological kidney damage.
• Investigating the expression of inflammatory and apoptotic markers (TNF-α, IL-6, NF-κB, caspase-3) in renal tissue.
• Evaluating the protective effects of a compound (crocin) on kidney structure and function using morphometric and immunohistochemical data.

Strengths

• Dataset includes multiple data modalities: physiological measurements, histopathological scoring, biochemical assays, and immunohistochemical analyses.
• Data is openly licensed under CC-BY-4.0, permitting reuse and redistribution.
• File size is 35.3 KB, indicating a compact and likely focused dataset.

Limitations

• Row count is unknown, which may limit suitability assessment for statistical modeling.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's scope is limited to a single, small-scale animal study with 35.3 KB of data.

Provenance

Source

figshare

Collection Method

Experimental data collected from a controlled laboratory study on Wistar rats.

Freshness

Last updated 2026-06-02 09:14:19; freshness should be verified.