Medication Adherence to PCSK9 Inhibitors from Systematic Review

Joseph E Blais provides raw and cleaned datasets from a systematic review and meta-analysis of observational studies on medication adherence to monoclonal antibody and small-interfering RNA PCSK9 inhibitors in clinical practice. The data includes study characteristics, participant information, and adherence outcomes extracted from literature searches across MEDLINE, EMBASE, PsycINFO, CINAHL Plus, and medRxiv. The dataset was last updated on April 21, 2026.

Use Cases

• Analyze medication adherence rates based on extracted adherence definitions and outcomes
• Compare study characteristics across different observational studies
• Meta-analysis of adherence outcomes for monoclonal antibody versus small-interfering RNA PCSK9 inhibitors
• Assess reporting completeness based on the EMERGE checklist mentioned in the description

Strengths

• Includes both raw datasets exported from Covidence review software and cleaned datasets processed for analysis
• Compiled from systematic searches across five major databases (MEDLINE, EMBASE, PsycINFO, CINAHL Plus, medRxiv)
• Contains a compressed EndNote library of references cited in the systematic review

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect temporal and publication bias inherent to the systematic review's source literature

Provenance

Source

Joseph E Blais via figshare

Collection Method

Extracted from studies identified through systematic literature search and review management software Covidence

Freshness

Last updated 2026-04-21 00:51:50