Noriko Nakamura's dataset from a 2026 figshare manuscript compares in vitro follicle growth in 2D and 3D culture models. The data likely contains measurements of follicle growth, estradiol secretion, and gene expression for preantral follicles obtained from postnatal days 7 and 16 mice. This dataset supports research into standardizing reproductive toxicity assessment models.
Use Cases
- Compare follicle growth rates between 2D and 3D culture systems based on the described growth endpoints.
- Analyze hormone secretion patterns based on the described estradiol secretion data.
- Investigate gene expression markers of follicular development based on the described gene expression endpoints.
- Benchmark the reproducibility of in vitro folliculogenesis models for regulatory acceptance.
Strengths
- Dataset is associated with a peer-reviewed manuscript, providing methodological context.
- Uses multiple biological endpoints (growth, hormone secretion, gene expression) for comparison.
- Released under a permissive CC-BY-4.0 license for reuse.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count and file formats are unknown, which may limit suitability assessment.
- Data may reflect the specific experimental bias inherent to the described mouse model and culture conditions.
Provenance
- Source
- figshare, associated with a manuscript by Noriko Nakamura.
- Collection Method
- Experimental data from comparing 2D and 3D (alginate beads) culture models for preantral follicles isolated from mice.
- Time Range
- Experimental timeframe not specified; dataset metadata updated in 2026.
- Freshness
- Last updated 2026-05-04 20:13:31; freshness should be verified.
- Geography
- null