Sir Proteins Impede Access to Silent Chromatin in Saccharomyces cerevisiae

463.9 MB of processed genomic data files from three published studies (GSE147927, GSE243114, GSE69400) on chromatin accessibility in yeast. Zhuwei Xu published this supplementary dataset on figshare in March 2026. The data includes normalized ChIP-exo seq occupancy, nucleosome protection measured by M.EcoGII, and MNase-seq bigwig files.

Use Cases

• Visualize fragment occupancy patterns based on ChIP-exo seq bigwig files.
• Analyze nucleosome protection levels based on M.EcoGII footprint data.
• Compare chromatin accessibility profiles based on MNase-seq data.
• Investigate silencing at mating type loci and telomeres based on platform tags.

Strengths

• Data is derived from three published, peer-reviewed genomic studies (GSE147927, GSE243114, GSE69400).
• Files are processed and normalized for visualization in tools like IGV.
• Dataset size is 463.9 MB, indicating substantial processed genomic data.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect methodological bias inherent to the specific ChIP-seq and footprint techniques used.

Provenance

Source

figshare

Collection Method

Pre-processed and aligned published ChIP-seq data using fastp, Bowtie2, SAMtools, and BEDTools.

Freshness

Last updated 2026-03-17 16:48:27.