JY5 Formula: Experimental Data on Liver Fibrosis Treatment in Rodent Models

A study by Yadong Fu, last updated in May 2026, investigates a novel Chinese medicine formula for treating liver fibrosis. The dataset likely contains experimental results from in vivo rat and mouse models and in vitro cell assays. It focuses on the anti-fibrotic effects of the JY5 formula, composed of salvianolic acid B, schisantherin A, and amygdalin.

Use Cases

• Validate the anti-fibrotic efficacy of the JY5 formula based on hydroxyproline content and collagen deposition measurements.
• Investigate the mechanism of hepatic stellate cell inactivation based on Notch signaling pathway data.
• Compare treatment effects across different liver fibrosis models based on data from CCl4- and bile duct ligation-induced models.

Strengths

• Dataset is under a permissive CC-BY-4.0 license for reuse.
• The study design includes both in vivo rodent models and in vitro cell activation models, as described.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 5.3 MB file size suggests a relatively small dataset.

Provenance

Source

Yadong Fu via figshare

Collection Method

Experimental data from pharmacological studies on rat, mouse, and LX-2 cell models.

Freshness

Last updated 2026-05-18 11:59:43; freshness should be verified.