JY5 Formula: Experimental Data on Anti-Fibrotic Effects in Rodent Models

A research dataset supporting a study on a novel Chinese medicine formula for liver fibrosis. The data likely contains experimental results from in vivo rat and mouse models and in vitro cell assays. The dataset was authored by Yadong Fu, shared under a CC-BY-4.0 license, and last updated in May 2026.

Use Cases

• Validate the anti-fibrotic efficacy of the JY5 formula based on hydroxyproline content and collagen deposition measurements.
• Analyze the relationship between JY5 components and hepatic stellate cell activation based on in vitro model data.
• Investigate the inhibition of the Notch signaling pathway as a mechanism of action based on the described experimental results.

Strengths

• Dataset is associated with a specific, peer-reviewed research study described in detail.
• Shared under a permissive CC-BY-4.0 license allowing for reuse and modification.
• File size is 8.1 MB, indicating a focused and likely manageable dataset.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analysis.
• The description focuses on the study narrative; the exact structure and variables of the data files are unspecified.

Provenance

Source

figshare, authored by Yadong Fu.

Collection Method

Generated from laboratory experiments using carbon tetrachloride- and bile duct ligation-induced liver fibrosis models in rats and mice, and an in vitro LX-2 cell activation model.

Time Range

Experimental timeframe not specified; dataset metadata updated May 2026.

Freshness

Last updated 2026-05-18 11:59:44; freshness should be verified.

Geography

Geographic origin of the research not specified.