De Novo Engineered Living Materials via ELP-Mediated Self-Assembly

Sarah B. Browning engineered Escherichia coli to display elastin-like polypeptides (ELPs), creating self-assembling living materials. The dataset, last updated on 2026-05-28, likely contains experimental results from tuning ELP polarity to generate assemblies from micrometer to centimeter scales. It includes data on controllable flocculation, filtration time reduction by more than 3-fold, and maintained ethanol production in small-scale fermentation.

Use Cases

• Optimizing genetic design rules for scalable self-assembly based on ELP sequence polarity.
• Modeling metabolic activity preservation in engineered cellular assemblies.
• Benchmarking filtration efficiency improvements in fermentation processes based on controllable flocculation.
• Evaluating the portability of self-assembly platforms across different genetic backgrounds and inducible expression systems.

Strengths

• Demonstrates a 3-fold reduction in filtration time in fermentation settings.
• Shows assemblies spanning micrometer- to centimeter-length scales.
• Includes data on maintained ethanol production performance comparable to a parental strain.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Experimental engineering of E. coli to display elastin-like polypeptides.

Freshness

Last updated 2026-05-28 13:38:25