TAT.ARC Treatment in Mouse Ischemic Stroke: Infarct Volume and Neuronal Density Data

A dataset from a study where mice were subjected to 60 minutes of middle cerebral artery occlusion (MCAo). Mice were treated with TAT.ARC or control protein 3 hours after ischemia onset and perfused after 72 hours. The data likely contains indirect lesion volume assessments, striatal area measurements, and neuronal densities within the striatum, based on coronal brain slices analyzed using a mouse brain atlas.

Use Cases

• Modeling the neuroprotective effects of TAT.ARC protein based on post-treatment infarct volume data.
• Analyzing correlations between striatal area measurements and neuronal densities in a mouse stroke model.
• Comparing indirect lesion volumes between treatment and control groups at specific brain coordinates.

Strengths

• Data is derived from a controlled experimental protocol with a defined 60-minute ischemia and 72-hour observation period.
• Analysis references specific brain atlas coordinates (a1 to a5) for consistent slice selection.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

paperswithcode

Collection Method

Experimental data from a study on delayed TAT.ARC administration in a mouse MCAo model.