Derbesiamides A–E: Cyclic Depsipeptides from Pedobesia Green Algae

A 2026 study by Towa Tsukamoto reports five cyclic depsipeptides, derbesiamides A–E, isolated from the green alga Pedobesia sp. The dataset, shared on figshare, includes structural data determined by NMR and HRESI-TOFMS analyses, with absolute configurations established via Marfey's analysis and LC–MS/MS. It expands the known chemical diversity of the Derbesiaceae family of marine algae.

Use Cases

• Identify novel bioactive compounds based on the reported cyclic depsipeptide structures.
• Train or validate computational models for NMR or mass spectrometry data interpretation.
• Compare secondary metabolite profiles across different families of Bryopsidales green algae.
• Support chemical ecology studies on the role of distinctive metabolites in marine organisms.

Strengths

• Structures were established using extensive NMR and HRESI-TOFMS analyses.
• Absolute configurations were determined by Marfey's analysis and further resolved for specific residues via synthetic comparison.
• The dataset is focused on a previously underexplored family (Derbesiaceae) of green algae.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset size is 67.1 MB, suggesting a relatively small-scale chemical study.

Provenance

Source

Towa Tsukamoto via figshare.

Collection Method

Chemical isolation and structural elucidation from Pedobesia sp. algae samples.

Freshness

Last updated 2026-05-18 14:05:00; freshness should be verified.