Determinants of Sarcopenia in Cirrhosis: Systematic Review and Meta-Analysis Data

Damian Harding's dataset compiles evidence from a systematic review and meta-analysis on factors associated with sarcopenia in patients with liver cirrhosis. It aggregates data from 39 studies comprising 5,654 individuals, sourced from PubMed, Embase, and Google Scholar up to June 2023. The dataset includes factors such as age, sex, BMI, MELD score, and serum biomarkers.

Use Cases

• Identifying risk factors for sarcopenia in cirrhosis based on demographic and clinical variables mentioned in the description
• Training models to predict sarcopenia likelihood based on factors like MELD score and serum biomarkers
• Conducting secondary meta-analyses on the association between specific variables (e.g., TNFα, IL-6) and muscle depletion

Strengths

• Aggregates data from 39 studies with a total of 5,654 individuals, providing a substantial evidence base
• Systematic review methodology ensures a structured and replicable collection of relevant studies
• Includes a range of associated factors such as age, sex, BMI, MELD score, and serum concentrations

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment for large-scale modeling

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of studies retrieved from PubMed, Embase, and Google Scholar.

Time Range

Studies from inception to June 2023.

Freshness

Last updated 2026-05-06 21:48:47; freshness should be verified