Dextran-DNA Nanogel Enhances Antifungal Peptide Efficacy: Raw Data

A 51.6 KB Excel dataset contains raw data from a study on a novel antifungal peptide delivery system. Dextran-functionalized DNA nanogels encapsulated GK17 peptide at 85.3% ± 4.32% efficiency and enabled sustained release over 7 hours. The data likely supports findings that this nanogel reduced cytotoxicity and eradicated Candida biofilms at lower peptide concentrations.

Use Cases

• Analyze nanogel encapsulation efficiency based on the reported 85.3% ± 4.32% loading rate
• Model sustained drug release kinetics based on the 7-hour release profile mentioned
• Compare antifungal efficacy against planktonic and biofilm Candida species based on the described 8-fold and 2-fold lower peptide concentration requirements
• Evaluate cytotoxicity reduction in therapeutic concentrations based on the significant reduction (P < 0.001) noted

Strengths

• Dataset includes specific quantitative results like 85.3% ± 4.32% encapsulation efficiency
• Study reports statistically significant outcomes (P < 0.001) for cytotoxicity and biofilm reduction
• Data is associated with a peer-reviewed research publication methodology described in detail

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect experimental bias inherent to the specific laboratory model described

Provenance

Source

figshare

Collection Method

Likely generated from laboratory experiments measuring nanogel properties, antifungal activity, and murine model outcomes.

Freshness

Last updated 2026-05-22 02:19:10; freshness should be verified