West Nile and Usutu Virus NS1 Glycoprotein Properties with In Vitro and Clinical Data

A 25.7 MB dataset from figshare, last updated on 2026-04-29, containing experimental results comparing the nonstructural protein 1 (NS1) of West Nile and Usutu viruses. The data, authored by Justine Revel, includes findings on NS1 secretion levels, thermal stability, and impact on blood-brain barrier integrity from in vitro, in vivo, and clinical approaches.

Use Cases

• Compare viral protein secretion and stability based on in vitro assay results mentioned in the description
• Model neurovirulence mechanisms based on data about blood-brain barrier disruption
• Investigate host immune response modulation based on transcriptional response data from endothelial cells
• Analyze correlations between serum NS1 levels and clinical neurological symptoms

Strengths

• Includes data from multiple experimental approaches: in vitro, in vivo, and clinical, as stated in the description
• File size is 25.7 MB, indicating a focused and manageable dataset
• Released under a permissive CC-BY-4.0 license, facilitating reuse

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Description metadata is limited; actual data quality requires manual inspection after download

Provenance

Source

figshare

Collection Method

Combined in vitro, in vivo, and clinical approaches, as described

Freshness

Last updated 2026-04-29 17:40:06; freshness should be verified