Lysine Fumarylation Sites and Enzymatic Pathways in Escherichia coli

Chen Chen's dataset documents the discovery of lysine fumarylation (Kfu), a post-translational modification in bacteria. It contains 857 endogenous Kfu sites identified in Escherichia coli using mass spectrometry and enzymatic pathway details. The dataset was last updated on April 10, 2026.

Use Cases

• Mapping protein modification sites based on mass spectrometry data
• Analyzing enzymatic regulation pathways for fumaryl-CoA synthesis and transfer
• Investigating metabolic signaling links to stress response pathways

Strengths

• 857 endogenous lysine fumarylation sites mapped
• Enzymatic pathway details for SucC–SucD, SpeG, and CobB included
• Data validated through chromatographic retention and MS/MS fragmentation comparisons

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Data is limited to Escherichia coli, a single bacterial species

Provenance

Source

figshare

Collection Method

Open-search mass spectrometry, antibody enrichment, and metabolic tracing

Freshness

Last updated 2026-04-10 06:05:29