Mangotoxin Biosynthetic Operon Data for Acetylenase MboA

A figshare text dataset by Edward D. Badding, last updated on 2026-04-28. It contains research data and findings on the discovery of the enzyme MboA, which catalyzes alkyne formation in the biosynthesis of the toxin mangotoxin. The dataset includes a crystal structure analysis of Fe(II)₂-MboA, revealing a short Fe–Fe distance.

Use Cases

• Study the catalytic mechanism of alkyne formation based on the described iterative desaturation process.
• Analyze the structural basis for C(sp²)–H bond activation based on the crystal structure data of Fe(II)₂-MboA.
• Investigate the functional role of redox partners in enzyme catalysis based on the interaction between MboA and MboB.
• Perform bioinformatics analysis of biosynthetic operons based on the discovery approach mentioned in the description.

Strengths

• Includes crystal structure data revealing an unexpectedly short Fe–Fe distance.
• Dataset size is 2.4 MB, facilitating quick download and inspection.
• Released under the CC-BY-NC-4.0 license, allowing for non-commercial reuse with attribution.

Limitations

• Row count and column definitions are unknown, limiting suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect the specific experimental and bioinformatics bias inherent to the source study.

Provenance

Source

figshare

Collection Method

Likely contains data generated from bioinformatics analysis, enzyme assays, and X-ray crystallography as described.

Freshness

Last updated 2026-04-28 20:45:26; freshness should be verified.