CIL56 Analogs: Ferroptotic and Necrotic Cell-Death Screening Data

Kenichi Shimada's dataset, published on figshare in March 2026, investigates the heterogeneous cell-death programs induced by the small molecule CIL56 and its structural analogs. The 83.0 KB XLSX file contains results from a phenotypic suppressor screen and target prediction analysis to resolve ferroptotic and necrotic death mechanisms.

Use Cases

• Classifying small-molecule death phenotypes based on the described ferroptotic and necrotic activities.
• Prioritizing candidate protein targets based on shared ligand-based target predictions mentioned in the description.
• Analyzing suppressor compound efficacy based on the distinct sets of molecules that selectively attenuate different death modalities.
• Integrating phenotypic screening with suppressor classification to improve mechanistic interpretation, as described.

Strengths

• Dataset is focused on a specific mechanistic investigation of CIL56 and related analogs.
• File size is 83.0 KB, indicating a compact and likely focused dataset.
• License is clearly defined as CC-BY-NC-4.0.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, authored by Kenichi Shimada.

Collection Method

Likely contains experimental results from phenotypic screening and suppressor classification.

Time Range

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Freshness

Last updated 2026-03-24 17:06:19; freshness should be verified.

Geography

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