562 Functionally Characterized Diterpene Synthases for Biosynthesis Research

562 functionally characterized diterpene synthases (diTPSs) compiled from previous studies form a database for synthetic biology. The dataset, created by Lei Zhang and last updated in 2026, supports bioinformatic analysis of catalytic mechanisms and product diversity. It is provided as a 256.2 KB Excel file under a CC-BY-NC-4.0 license.

Use Cases

• Phylogenetic analysis of enzyme families based on the compiled diTPS sequences.
• Identifying rate-limiting enzymes for metabolic engineering of diterpenoid pathways.
• Studying structure-function relationships in diterpene synthases to predict product diversity.
• Screening for novel diTPS candidates to overcome bottlenecks in large-scale production.

Strengths

• Compiles 562 functionally characterized enzymes, providing a substantial reference set.
• Focuses on a specific, rate-limiting enzyme class critical for diterpenoid biosynthesis.
• Includes integrated bioinformatic analyses of catalytic mechanisms and phylogenetic distribution.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is static and was last updated in 2026; freshness should be verified for ongoing research.

Provenance

Source

figshare

Collection Method

Compiled from previous studies as described in an accompanying review article.

Freshness

Last updated 2026-05-30 03:33:22