Reaction Pathways of an Azomethine Ylide Precursor with Different Double Bonds

Experimental data from mechanistic studies on reactions of N-methoxymethyl-N-(trimethylsilyl)methylbenzylamine with various unsaturated compounds. The dataset, authored by Yuliang Wei and last updated in April 2026, investigates how nucleophilicity and electrophilicity influence reaction pathways, shifting from concerted cycloadditions to stepwise annulations.

Use Cases

• Modeling reaction mechanisms based on electronic characteristics of double bonds described in the study.
• Predicting product structures from unsymmetric azomethine ylide precursors as guided by the research.
• Analyzing the influence of catalyst type on reaction rates for the described precursor.
• Training models to classify reaction pathways (concerted vs. stepwise) based on nucleophilicity data.

Strengths

• Dataset size is 5.2 MB, indicating a focused and manageable collection.
• Mechanistic insights were systematically investigated using a geminally dideuterium-labeled precursor as a probe.
• The study provides explicit guidance on structural prediction of products from the precursor.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Experimental studies using a deuterium-labeled precursor probe.

Time Range

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Freshness

Last updated 2026-04-30 12:08:42; freshness should be verified.

Geography

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