183 individuals' eosinophil and 192 individuals' CD4+ naïve T cell methylation data from the Saguenay–Lac-Saint-Jean Asthma Family Cohort. This dataset includes targeted sequencing data from a custom immune region panel (mccSeq) for studying genetic and environmental asthma factors. The data was authored by Catherine Laprise and last updated on 2026-04 25.
Use Cases
- Identify methylation biomarkers for asthma risk based on immune cell epigenomic data.
- Analyze epigenetic differences between eosinophil and CD4+ naïve T cell populations.
- Study gene-environment interactions in asthma using cohort methylation profiles.
- Validate custom mccSeq panel performance for targeted immune region sequencing.
Strengths
- Data from a defined familial asthma cohort, providing a controlled genetic background.
- Includes two specific immune cell types: eosinophils (183 individuals) and CD4+ naïve T cells (192 individuals).
- Uses a custom targeted sequencing panel (mccSeq) designed for immune regions.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- Data may reflect geographic bias inherent to the Saguenay–Lac-Saint-Jean cohort.
Provenance
- Source
- Borealis Harvested Dataverse, authored by Catherine Laprise.
- Collection Method
- Targeted sequencing (mccSeq custom panel) performed on circulating immune cells.
- Time Range
- null
- Freshness
- Last updated 2026-04-25 04:15:20; freshness should be verified.
- Geography
- Saguenay–Lac-Saint-Jean region cohort.