Neuronal Survival Dose-Response Curves After Oxygen-Glucose Deprivation

Stefan Donath's dataset contains dose-response curves measuring the survival of primary mouse cortical neurons after oxygen-glucose deprivation (OGD). The data likely shows the effect of exogenous ARC protein transduction compared to a control treatment. It is derived from 4 independent experiments.

Use Cases

• Modeling dose-dependent neuroprotection based on ARC protein transduction levels.
• Comparing neuronal survival rates between ARC and control treatments after OGD.
• Analyzing the time course of cell survival 24 hours post-insult.

Strengths

• Data is based on 4 independent experiments, suggesting reproducibility.
• Experimental conditions are specified, including a 150-minute OGD period and analysis at 24 hours.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Last update date is unknown; freshness unverified.

Provenance

Source

Stefan Donath via paperswithcode

Collection Method

Primary mice cortical neuronal cultures subjected to oxygen-glucose deprivation (OGD).