Molecular dynamics simulation data investigating the transport mechanism of the mitochondrial carrier SLC25A51. The dataset was created by Shivansh Goyal and harvested by the Texas Data Repository, with a last update recorded on March 18, 2024. The data likely contains results from simulations of homology models in lipid bilayers, including binding site and gate dynamics information.
Use Cases
- Analyzing cardiolipin binding site interactions based on the three distinct sites mentioned in the description
- Modeling ligand-induced transport initiation based on the described electrostatic interaction between NAD+ and the protein pore
- Studying salt bridge gate dynamics in mitochondrial carriers based on the simulation data regarding matrix gate control
- Investigating substrate specificity for oxidized NAD+ based on the described binding selectivity mechanisms
Strengths
- Data is derived from molecular dynamics simulations, a standard computational method in structural biology
- Includes hypotheses tested via biochemical assays, suggesting experimental validation
- Last updated on 2024-03-18, indicating recent availability
Limitations
- Column-level documentation is absent; field semantics must be inferred after download
- Row count is unknown, which may limit suitability assessment
- Description metadata is limited; actual data quality requires manual inspection after download
Provenance
- Source
- Texas Data Repository Harvested Dataverse
- Collection Method
- Molecular dynamics simulations and biochemical assays
- Time Range
- null
- Freshness
- Last updated 2024-03-18 10:37:32
- Geography
- null