Keratograph Analysis of Steroid Eyedrops Before Glaucoma Surgery, 31 Patients

31 glaucoma patients were treated with loteprednol etabonate eyedrops for one week before trabeculectomy surgery. The study by Nikoly T. Fares measured ocular surface disease before and after surgery using questionnaires, clinical exams, and keratograph analysis. Results showed a high prevalence of ocular surface disease and significant postoperative changes in conjunctival hyperemia and tear breakup time.

Use Cases

• Analyzing the effect of preoperative steroid treatment on ocular surface parameters based on keratograph measurements.
• Modeling the relationship between Ocular Surface Disease Index scores and clinical signs like tear breakup time and conjunctival hyperemia.
• Investigating changes in noninvasive tear breakup time and bulbar redness before and after glaucoma surgery.
• Studying the prevalence of ocular surface disease in a cohort of glaucoma patients using multiple topical medications.

Strengths

• Includes data from 31 eyes of 31 patients with detailed pre- and post-operative measurements.
• Uses multiple assessment methods: Ocular Surface Disease Index questionnaire, clinical exams, and objective keratograph analysis.
• Reports specific statistical results, such as p-values for bulbar redness (p=0.013) and noninvasive tear breakup time (p=0.041).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect temporal/source bias inherent to paperswithcode, as it describes a single clinical study.

Provenance

Source

Nikoly T. Fares via paperswithcode.

Collection Method

Clinical study of glaucoma patients undergoing trabeculectomy, with data collected at baseline and two weeks post-surgery.