Iron Oxide Nanoparticle Toxicity Data from In Vitro and In Vivo Tests

A toxicological study presents data on the effects of iron oxide nanoparticles (NP Fe2O3). The research includes physicochemical characterization, cell viability assays using different cell lines, genotoxicity evaluations via the Allium cepa test and comet assay, and oxidative stress analyses in Danio rerio. The dataset likely contains results from these experiments, such as nanoparticle size (65.55 nm), polydispersity index (0.24), zeta potential (11.4 mV), and toxicity measurements across various concentrations.

Use Cases

• Modeling nanoparticle cytotoxicity based on concentration and physicochemical properties mentioned in the description
• Analyzing genotoxicity patterns from comet assay and Allium cepa test results described in the study
• Investigating oxidative stress biomarker responses (CAT, GPx, GST enzyme activity) in Danio rerio liver tissue
• Comparing in vitro and in vivo toxicity outcomes for iron oxide nanoparticles as outlined in the research

Strengths

• Includes specific physicochemical measurements: nanoparticle size of 65.55 nm, polydispersity index of 0.24, and zeta potential of 11.4 mV
• Reports experimental results from multiple assays: cell viability, comet assay, Allium cepa test, and enzymatic activity analysis
• Covers both in vitro (cell lines) and in vivo (Danio rerio) test models as described

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Last update date is unknown; freshness unverified

Provenance

Source

Tatiane Balbo Batista-Gallep

Collection Method

Experimental data from a study involving physicochemical characterization, cell viability assays, genotoxicity tests, and oxidative stress analyses.