Effects of Paraquat on SOD1 Transgenic Drosophila Flies

Experimental data on the effects of the herbicide paraquat on transgenic Drosophila flies expressing human SOD1 protein variants. The dataset includes results from 2,603 total flies across multiple genotypes, with SOD1 expressed in motor neurons, glial cells, or both. The data was published by Rafique Islam on the Papers with Code platform under an Open Access license.

Use Cases

• Analyze the lack of significant paraquat effect on SOD1 transgenic flies based on the described experimental results.
• Compare survival or response data across different genetic driver lines (D42Gal4, M1BGal4, D42+M1BGal4) based on the description.
• Study the interaction between specific human SOD1 mutations (A4V, G85R) and paraquat exposure based on the described genotypes.
• Benchmark genetic models of neurodegeneration against environmental toxin challenges based on the described experimental setup.

Strengths

• The description provides a precise total fly count of 2,603 individuals across all experimental groups.
• Specific experimental parameters are stated, including a 20 mM paraquat concentration and the use of five day-old male flies.
• The dataset is associated with a published research output on the Papers with Code platform.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Last update date is unknown; freshness unverified.

Provenance

Source

paperswithcode

Collection Method

Experimental study involving treatment of transgenic Drosophila flies with paraquat.