Systematic Reviews on Exercise Interventions for Pulmonary Hypertension

14 systematic reviews of randomized controlled trials evaluating exercise training, inspiratory muscle training, and combined training for pulmonary hypertension. The overview, authored by Natália Lopes Cardoso and last updated in May 2026, assessed methodological quality and certainty of evidence using AMSTAR-2 and GRADE. Findings indicate clinically significant improvements in functional capacity, measured by six-minute walk test distance and VO₂peak.

Use Cases

• Compare the efficacy of different exercise interventions based on the reported six-minute walk test and VO₂peak outcomes
• Assess the methodological quality of existing systematic reviews based on the AMSTAR-2 and GRADE evaluations mentioned
• Identify research gaps in pulmonary hypertension rehabilitation based on the overlap analysis of included reviews

Strengths

• Includes quantitative results for three intervention types, such as 6MWT distance increases of >48.5 m for exercise training
• Assesses methodological quality and certainty of evidence using standardized tools AMSTAR-2 and GRADE
• Protocol is registered with a PROSPERO identifier (CRD42025643615), indicating a structured review process

Limitations

• The dataset is a single 34.5 KB DOCX file, suggesting limited scope and no raw data tables
• Methodological quality of the included reviews was rated as critically low
• Column-level documentation is absent; field semantics must be inferred from the textual description

Provenance

Source

figshare

Collection Method

Overview of systematic reviews gathered from seven databases, with analysis conducted by independent reviewers.

Freshness

Last updated 2026-05-15 11:08:11; freshness should be verified