Effects of Space Flight on Mouse Brain Inflammasome Activation, 37-Day ISS Mission

37 days of spaceflight data from NASA's Rodent Research 1 Mission on the International Space Station from September 21st, 2014, to October 25th, 2014. The dataset contains results from Electrochemiluminescence Immunoassay (ECLIA) and Western Blot analyses of brain tissue from C57BL/6 mice, measuring inflammasome signaling proteins and cytokine levels. It was produced by the National Aeronautics and Space Administration and last updated in March 2026.

Use Cases

• Modeling the impact of microgravity on neuroimmune signaling based on inflammasome protein levels.
• Comparing cytokine expression profiles between spaceflight and ground control groups.
• Analyzing the correlation between spaceflight duration and innate immune response changes in brain tissue.

Strengths

• Data originates from a controlled NASA mission with a defined 37-day experimental timeframe.
• Includes results from two specific assay types: Western Blot and Electrochemiluminescence Immunoassay (ECLIA).
• Compares three distinct experimental groups: ISS flight, ground control, and baseline launch groups.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The data is stored in a BIN file format, which may require specialized tools for access.

Provenance

Source

National Aeronautics and Space Administration

Collection Method

Immunoblotting and Electrochemiluminescence Immunoassay of dissected mouse brain tissue from the Rodent Research 1 Mission.

Time Range

Experimental period from September 21st, 2014, to October 25th, 2014.

Freshness

Last updated 2026-03-13 20:10:25.366887; freshness should be verified.

Geography

International Space Station and corresponding ground control locations.