Electrospray Regime Performance in Micro- and Nano-Flow CE–ESI–MS

Experimental data benchmarks the cone-jet and pulsating electrospray regimes for capillary electrophoresis–mass spectrometry (CE–ESI–MS). The dataset, made available by Ryan M. O’Neal, includes results for trace-level metabolites, peptides, and proteome digests. It was last updated on 2026-05-02.

Use Cases

• Optimizing ionization conditions for trace-level metabolite analysis based on sensitivity and signal stability comparisons.
• Improving peptide and protein identification in proteomics workflows based on coverage and quantification completeness metrics.
• Selecting electrospray regimes for single-cell-scale analyses based on feature detection and protein group recovery results.

Strengths

• Dataset size is 1.6 MB, facilitating quick download and inspection.
• Results include specific performance metrics, such as a ~2-fold sensitivity increase and ~50% more peptide identifications.
• Data is provided in an XLSX format, which is widely accessible for analysis.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely contains experimental results from benchmarking CE–ESI–MS performance.

Freshness

Last updated 2026-05-02 13:04:04; freshness should be verified.