Embryology and Clinical Outcomes After Sperm Preparation Using ZyMōt Versus DGC

A retrospective study of 2,267 ICSI cycles (1,091 using ZyMōt microfluidic sorting and 1,176 using density gradient centrifugation) compares fertilization, blastocyst development, euploidy, and pregnancy outcomes. The data was authored by Hanna Balakier and last updated on May 12, 2026. It includes statistical comparisons for fertilization rates (81.0% vs. 78.7%), day 5 blastocyst proportions (25.6% vs. 18.3%), and cumulative clinical pregnancy rates in donor and non-donor groups.

Use Cases

• Compare fertilization rates based on sperm preparation method (ZyMōt vs. DGC)
• Analyze blastocyst developmental potential based on sperm DNA fragmentation and motility
• Investigate clinical pregnancy and live birth outcomes stratified by oocyte source (donor vs. non-donor)
• Assess embryo euploidy rates in relation to sperm processing technique across female ages 20-40

Strengths

• Includes 2,267 total ICSI cycles, providing a substantial sample size for comparison
• Reports specific, statistically significant outcome percentages (e.g., fertilization, blastocyst rates)
• Uses hierarchical multivariate regression models adjusting for female age, male age, and infertility diagnosis

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

Hanna Balakier via figshare

Collection Method

Retrospective study of ICSI cycles

Freshness

Last updated 2026-05-12 06:27:51; freshness should be verified