Emergence of carbapenem-resistant putative hypervirulent <i>Klebsiella pneumoniae</i> ST14

A multicenter genomic epidemiology study of carbapenem-resistant hypervirulent Klebsiella pneumoniae isolates from 19 tertiary-care hospitals across Türkiye between 2018 and 2023. The dataset includes whole-genome sequencing results for investigating resistance and virulence determinants, plasmid replicon profiles, and phylogenetic relationships. It was authored by Cansel Vatansever and last updated in April 2026.

Use Cases

• Tracking clonal shifts in bacterial populations based on the reported transition from ST2096 to ST147 dominance
• Analyzing the co-carriage of resistance genes like blaNDM-5 and blaOXA-48 in specific lineages
• Investigating hybrid plasmid structures and their novel resistance determinants such as rmtF1 and arr-2
• Monitoring temporal trends in the proportion of CR-hvKp among CR-Kp isolates over a five-year period

Strengths

• Data spans a five-year time range from 2018 to 2023
• Sourced from a multicenter study across 19 tertiary-care hospitals in Türkiye
• Includes long-read sequencing results revealing a specific 364-kb hybrid plasmid
• Reports specific temporal trends, such as the CR-hvKp proportion increasing from 20.7% to 33.1%

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download

Provenance

Source

figshare

Collection Method

Whole-genome sequencing of clinical isolates collected from 19 hospitals

Time Range

2018 to 2023

Freshness

Last updated 2026-04-16 03:26:53

Geography

Türkiye