Díaz, Diana presents data on the synthesis and biological evaluation of novel mesoporous silica nanoparticles functionalized with organotin(IV) complexes and targeting ligands. The dataset likely contains results from cytotoxicity assays performed on cancer cell lines (HeLa and MCF-7) and non-cancerous cell lines (Hek 293T and RPE-1). The data was last updated on 2026-06-28.
Use Cases
- Compare cytotoxic activity of novel tin-functionalized nanoparticles based on the described in vitro assays.
- Evaluate cancer cell targeting selectivity based on the described biotin and folic acid ligand conjugation.
- Benchmark novel compounds against conventional treatments based on the described comparison to cisplatin.
Strengths
- Data includes results from cytotoxicity assays on four distinct cell lines, enabling selectivity analysis.
- Nanoparticle systems were characterized using multiple methods, including microscopy and spectroscopy.
- The described compounds demonstrated higher cytotoxic activity than cisplatin in the reported evaluation.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- Freshness should be verified as the last update date is in the future (2026-06-28).
Provenance
- Source
- e-cienciaDatos Harvested Dataverse
- Collection Method
- Synthesized and characterized in a laboratory setting.
- Freshness
- Last updated 2026-06-28 04:10:08