Enhancement of tobramycin and amikacin activities by co-encapsulation in liposomal-thymoqu

A figshare dataset authored by Raghad R. Alzahrani in April 2026 presents results from a study co-encapsulating aminoglycoside antibiotics tobramycin and amikacin with thymoquinone in liposomes. The data likely contains characterization metrics like nanoparticle size, zeta potential, and encapsulation efficiency, alongside biological assay results for antimicrobial activity and cell viability. The dataset includes 9.6 MB of files in TIFF and DOCX formats.

Use Cases

• Analyze nanoparticle formulation properties based on size, polydispersity, and zeta potential data
• Evaluate enhanced antibacterial efficacy based on MIC/MBC reduction and time-kill assay results
• Assess biofilm inhibition potential based on percentage inhibition data
• Study cytocompatibility of formulations based on cell viability percentages in HK-2 and HEK293T cells

Strengths

• Includes specific characterization metrics: nanoscale size around 100 nm, polydispersity index 0.1–0.2, and zeta potential around -60 mV
• Reports significant biological outcomes: MIC reduction by up to 31–500-fold against resistant isolates and biofilm inhibition up to 90–98%
• Provides cytocompatibility data with cell viability ranging from 63–100%

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect experimental bias inherent to the specific laboratory study

Provenance

Source

figshare

Collection Method

Data generated from laboratory experiments characterizing liposomal formulations and conducting biological assays.

Freshness

Last updated 2026-04-10 09:00:42; freshness should be verified