Prednisolone Dissolution Data from Spray-Dried Arabinoxylan Microspheres

Four formulations (F1–F4) of spray-dried arabinoxylan microspheres loaded with prednisolone were characterized for drug loading, entrapment efficiency, and dissolution. Drug loading ranged from 3.7% to 15.63% w/w, and the best formulations (F3 and F4) achieved over 72% drug dissolution within 60 minutes. The dataset was created by Muniyandy Saravanan and last updated in April 2026.

Use Cases

• Modeling drug dissolution profiles based on formulation parameters like drug loading and entrapment efficiency.
• Comparing the performance of novel excipients (arabinoxylan) against commercial products using similarity factor (f2) analysis.
• Investigating the relationship between physicochemical characterization (SEM, FTIR, DSC) and in vitro drug release outcomes.

Strengths

• Quantitative results for four distinct formulations (F1-F4) are provided, including specific drug loading percentages (3.7% to 15.63% w/w).
• Multiple analytical techniques (NMR, FTIR, SEM, DSC) were used for physicochemical characterization, as described.
• Dissolution performance is directly compared to a pure drug standard (26.8%) and a commercial tablet (49.9%).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (351.7 KB), indicating a limited experimental scope.

Provenance

Source

figshare

Collection Method

Experimental data from the extraction of arabinoxylan from ispaghula husk and the subsequent preparation and evaluation of spray-dried microspheres.

Freshness

Last updated 2026-04-20 09:47:17; freshness should be verified.