ENIGMA SCZ MRS: Site-Specific GWAS Summary Statistics for Schizophrenia

A 69.9 MB ZIP file of leave-one-out site-specific genome-wide association study (GWAS) summary statistics, necessary for running the ENIGMA SCZ MRS study. The dataset was authored by Nadine Parker and last updated on April 9, 2026. Instructions for use are provided on a linked GitHub repository.

Use Cases

• Conducting multi-site GWAS meta-analyses based on the described leave-one-out methodology.
• Calculating polygenic risk scores (MRS) for schizophrenia using site-specific summary statistics.
• Assessing genetic signal heterogeneity across different research sites as implied by the dataset's purpose.

Strengths

• Dataset is 69.9 MB, indicating a manageable download size.
• Released under a permissive CC-BY-4.0 license.
• Associated with the established ENIGMA consortium for psychiatric genetics.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, authored by Nadine Parker.

Collection Method

Likely generated as part of the ENIGMA SCZ MRS study, using a leave-one-out site-specific GWAS approach.

Time Range

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Freshness

Last updated 2026-04-09 11:29:22; freshness should be verified.

Geography

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