ESBL Meta-Analysis: Kidney Phosphoproteomic and Omics Data from Mouse and Rat Models

A collection of nine integrated databases from the Epithelial Systems Biology Laboratory archiving published omic data related to kidney biology. The 16.3 MB ZIP file contains web architecture for accessing phosphoproteomic data, cell-type markers, RNA-seq counts, and protein signaling networks, primarily from mouse and rat models. The resource was made available by the Knepper Lab at the NHLBI, NIH, with a last documented update on April 30, 2026.

Use Cases

• Identify cell-type selective markers based on the listed mouse kidney marker database.
• Analyze vasopressin-regulated phosphorylation sites based on the mapped molecular function portals.
• Study osmoregulation in mammalian systems based on the database of osmo-regulated proteins.
• Investigate primary cilium composition based on the mouse mIMCD cell proteome data.

Strengths

• Integrates nine distinct thematic databases into a single 16.3 MB resource.
• Provides a documented web interface for search, browse, and download capabilities.
• Originates from an authoritative NIH laboratory (Epithelial Systems Biology Laboratory).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The data is packaged in a custom web architecture (ZIP), requiring extraction and navigation.

Provenance

Source

Epithelial Systems Biology Laboratory (DIR, NHLBI, NIH), Knepper Lab.

Collection Method

Archival of previously published omic data.

Time Range

Covers published studies up to the archive date; specific temporal range not stated.

Freshness

Last updated 2026-04-30 17:21:19.

Geography

Laboratory-based research, primarily using mouse and rat models.