SEPHS2 and GPX Biomarker Images for Recurrent Pregnancy Loss Study

A clinical study of 100 women with idiopathic recurrent pregnancy loss and 100 healthy controls, conducted by Mai M. Shaker. Data includes images quantifying SEPHS2 gene expression via qRT-PCR and plasma GPX levels via ELISA, with results indicating a significant association between elevated SEPHS2, reduced GPX, and pregnancy loss. The dataset was last updated on April 16, 2026.

Use Cases

• Training image analysis models to quantify gene expression patterns from qRT-PCR results.
• Correlating visual biomarker data with clinical outcomes for recurrent pregnancy loss.
• Developing prognostic models for pregnancy loss risk based on SEPHS2 and GPX biomarker levels.

Strengths

• Includes data from a case-control study with 200 total participants (100 cases, 100 controls).
• Reports specific, statistically significant findings (e.g., mean fold change for SEPHS2: 14±11.4 vs. 5±8).
• Data is shared under a permissive CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 1.6 MB size suggests a small dataset, potentially limiting model training.

Provenance

Source

Mai M. Shaker via figshare.

Collection Method

SEPHS2 gene expression was quantified using qRT-PCR, and plasma GPX levels were measured using ELISA.

Freshness

Last updated 2026-04-16 09:27:31; freshness should be verified.