Priestia megaterium SR7: Evidence for Pyruvate Node Metabolons

Priestia megaterium SR7, a supercritical CO2-tolerant extremophile, is the subject of this dataset. The data provides in vitro and in silico evidence for the formation of metabolons, enzyme complexes surrounding the pyruvate node, which may regulate carbon flux. The dataset was authored by Nathaphon Yu King Hing and last updated on June 2, 2026.

Use Cases

• Modeling carbon flux regulation based on proposed metabolon formation.
• Identifying potential protein-protein interaction sites based on in silico simulations.
• Designing metabolic engineering strategies based on enzyme organization insights.
• Analyzing metabolite channeling efficiency based on isotopic labeling experiments.

Strengths

• Data includes multiple experimental lines of evidence: cross-linking proteomics, in silico simulations, and isotopic labeling.
• Dataset size is 36.2 MB, facilitating relatively quick download and inspection.
• License is CC-BY-NC-4.0, permitting non-commercial reuse with attribution.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Generated from cross-linking experiments, proteomics, in silico simulations, and 13C isotopic labeling of the bacterium Priestia megaterium SR7.

Freshness

Last updated 2026-06-02 12:19:36; freshness should be verified.