Excitatory Amino Acid Neurotoxicity in the Developing Brain: A Neuroscience Review

John W. McDonald of Johns Hopkins University authored a review paper on excitatory amino acid neurotransmitters in central nervous system development. The paper discusses their roles in synaptic plasticity, learning, memory, and the continuum from underactivation disrupting development to overactivation causing neuronal injury. The dataset appears to be the text of this academic paper, sourced from the paperswithcode platform.

Use Cases

• Text mining for relationships between EAA neurotransmitters and synaptic plasticity based on the detailed biological description.
• Analyzing the conceptual model of a continuum from underactivation to overactivation of EAA receptors described in the text.
• Extracting information on the changing roles of NMDA and non-NMDA receptors in excitotoxic injury across postnatal development stages.
• Building a knowledge graph of neurodevelopmental processes and molecular mechanisms involving excitatory amino acids.

Strengths

• Authored by a researcher from a recognized institution, Johns Hopkins University.
• The description provides a detailed, domain-specific narrative on a focused neuroscience topic.

Limitations

• Row count and file size are unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

Johns Hopkins University / paperswithcode

Collection Method

Likely a published academic paper or review article.