Chemoproteomic Mapping of Asparagine and Glutamine Sites in Yeast and Candida Albicans

A 122.7 KB Excel dataset published on figshare by Benjamin Emenike in April 2026. It contains results from a chemoselective palladium-mediated dehydration method enabling proteome-wide mapping of asparagine and glutamine sites. The data includes sites impacted by deamidation and N-glycosylation, expanding the known N-glycoproteome in yeast and capturing dynamic glycosylation remodeling in Candida albicans.

Use Cases

• Identify novel N-glycosylation sites in yeast based on the described inverse chemoproteomic framework.
• Analyze dynamic changes in glycosylation patterns during Candida albicans morphogenesis based on comparative profiling data.
• Study sites protected from chemical modification by deamidation based on the reported PTM-mediated protection data.
• Validate or expand traditional glycopeptide enrichment results based on the identification of low-abundance or noncanonical motifs.

Strengths

• Dataset is 122.7 KB, indicating a focused and manageable size for analysis.
• Data was generated using a novel chemoselective method enabling first proteome-wide mapping of Asn/Gln sites.
• Includes results from both lysates and living cells, as mentioned in the description.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

figshare

Collection Method

Chemoproteomic data generated via a palladium-mediated dehydration transformation and inverse chemoproteomic framework.

Time Range

Experimental timeframe not specified.

Freshness

Last updated 2026-04-09 10:30:13; freshness should be verified.

Geography

null