Chemoproteomic Mapping of Asparagine and Glutamine Sites in Yeast and Candida Albicans

A 1.3 MB XLSX file from figshare, authored by Benjamin Emenike and last updated in April 2026. The dataset contains chemoproteomic data generated using a palladium-mediated dehydration method to map asparagine and glutamine sites across proteomes. It includes results from lysates and living cells of yeast and Candida albicans, revealing sites impacted by deamidation and N-glycosylation.

Use Cases

• Identify N-glycosylation sites missed by traditional enrichment methods based on the described inverse chemoproteomic framework.
• Analyze dynamic remodeling of glycosylation patterns during Candida albicans morphogenesis based on comparative profiling data.
• Map residue accessibility and PTM-linked site dynamics across biological states based on the dehydration-to-nitrile platform.
• Investigate sites protected from chemical labeling by deamidation or N-glycosylation based on the PTM-mediated protection reporting.

Strengths

• Dataset is 1.3 MB, indicating a manageable file size for analysis.
• Data was generated using a novel, chemoselective method for proteome-wide interrogation of asparagine and glutamine.
• Includes results from living cells, suggesting biological relevance.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Chemoproteomic data generated via palladium-mediated dehydration and mass spectrometry.

Time Range

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Freshness

Last updated 2026-04-09 10:30:14; freshness should be verified.

Geography

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