Chemoproteomic Mapping of Asparagine and Glutamine Sites in Yeast and Candida

A chemoproteomic dataset mapping chemically addressable asparagine and glutamine sites in cell lysates and living organisms. The data was generated by Benjamin Emenike using a palladium-mediated dehydration method and was last updated in April 2026. It includes results from yeast and Candida albicans experiments.

Use Cases

• Identify N-glycosylation sites in yeast proteomes based on the described inverse chemoproteomic framework.
• Analyze dynamic remodeling of glycosylation patterns during Candida albicans morphogenesis based on comparative profiling data.
• Map post-translational modification-mediated protection of asparagine and glutamine sites based on the reported nitrile formation reactivity.
• Discover noncanonical or low-abundance glycoproteome candidates missed by traditional enrichment methods based on the described platform.

Strengths

• Data is derived from a novel chemoselective method enabling proteome-wide mapping of asparagine and glutamine sites.
• The dataset includes results from experiments in both lysates and living cells.
• File size is 957.3 KB, indicating a focused and manageable dataset.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Last updated 2026-04-09 10:30:12; freshness should be verified.

Provenance

Source

figshare, author Benjamin Emenike.

Collection Method

Generated via a chemoselective palladium-mediated dehydration method converting amides to nitriles for proteome-wide mapping.

Time Range

Experimental timeframe not specified.

Freshness

Last updated 2026-04 09.

Geography

Laboratory-based biological data, specific geography not indicated.