Factors associated with drug-resistant epilepsy in adults from Southern Kazakhstan

37% of the 300 epilepsy patients in this cohort were classified as drug-resistant. This dataset, authored by Gulzira Baimakhanova and last updated in April 2026, contains clinical, neuroimaging, and cognitive assessment data from a retrospective cross-sectional study in Southern Kazakhstan. The research identified early seizure onset, frequent daily seizures, and MRI abnormalities as significant factors associated with drug resistance.

Use Cases

• Predicting drug-resistant epilepsy risk based on clinical patterns like age of seizure onset and seizure frequency.
• Analyzing the association between brain imaging abnormalities (MRI) and treatment resistance in epilepsy.
• Investigating the relationship between cognitive performance (MoCA test scores) and epilepsy drug resistance.
• Identifying socio-demographic and clinical profiles associated with drug-sensitive versus drug-resistant patient groups.

Strengths

• Includes data from 300 patients with detailed clinical, neuroimaging, and cognitive assessments.
• Provides a specific prevalence figure (37%) for drug-resistant epilepsy within the studied cohort.
• Reports statistically significant associations, such as a 2.42 times increased risk of drug resistance linked to MRI abnormalities.

Limitations

• Row count and column-level documentation are unknown, which limits suitability assessment.
• Data is limited to a single region (Southern Kazakhstan), which may not be generalizable to other populations.
• The dataset is very small at 173.1 KB, indicating limited scope.

Provenance

Source

figshare, author Gulzira Baimakhanova

Collection Method

Retrospective analytical cross-sectional study using ILAE criteria for classification.

Time Range

null

Freshness

Last updated 2026-04-30 08:02:21; freshness should be verified.

Geography

Southern Kazakhstan