Factors Associated with Silent Cerebral Events During Atrial Fibrillation Ablation

A clinical study by Masafumi Harada of Fujita Health University investigates predictors of silent cerebral events (SCEs) in patients undergoing atrial fibrillation ablation. The dataset includes 285 patients on uninterrupted oral anticoagulation, with 66 patients (23.1%) showing SCEs detected via post-procedural brain MRI. It compares clinical characteristics and procedure-related parameters like left-atrial dimension and activated clotting time kinetics between patient groups.

Use Cases

• Predicting silent cerebral event risk based on left-atrial dimension and activated clotting time parameters mentioned in the description
• Comparing the impact of different oral anticoagulants (NOACs vs. VKA) on intra-procedural coagulation metrics
• Analyzing associations between patient demographics (age, AF type) and clinical scores (CHADS2/CHA2DS2-VASc) with neurological event incidence

Strengths

• Includes data from 285 patients, providing a substantive clinical cohort
• Reports specific incidence rate of 23.1% for silent cerebral events
• Compares multiple clinical and procedural variables like age, AF type, and activated clotting time

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Last update date is unknown; freshness unverified

Provenance

Source

Fujita Health University

Collection Method

Clinical study of patients undergoing catheter ablation for atrial fibrillation, with data collected from brain MRI and procedural parameters.