Extraction Method Validation Data for Opium Alkaloids in Poppy Seed Beverages

A dataset likely containing validation results for a green analytical method to extract opium alkaloids from poppy seed beverages. The method, developed by Casado-Hidalgo, Gema, uses a hydrophobic natural deep eutectic solvent and was validated in 2025. It reports extraction efficiencies between 91 and 107 percent and low quantification limits.

Use Cases

• Validate green analytical chemistry methods based on reported extraction efficiencies and precision values.
• Benchmark miniaturised liquid-liquid extraction (m-LLE) techniques based on the described vortexing and centrifugation protocol.
• Compare the greenness of analytical methods using the AGREEprep metric scale score of 0.79 mentioned in the description.
• Study the application of hydrophobic natural deep eutectic solvents (HNADES) for analyte extraction from complex matrices.

Strengths

• Method validation results include specific extraction efficiencies between 91 and 107 percent for all analytes.
• Quantification limits are provided: 0.1 µg/mL for most analytes and 0.4 µg/mL for morphine.
• The greenness of the method is quantified with an AGREEprep metric scale score of 0.79.
• The description details a specific, rapid sample preparation protocol using 0.5 mL of sample and solvent.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analysis.
• The dataset appears to contain validation data for a specific method, which may limit generalizability.

Provenance

Source

e-cienciaDatos Harvested Dataverse

Collection Method

Likely contains experimental results from the development and validation of an analytical methodology.

Time Range

The dataset was last updated in 2025, but the temporal coverage of the underlying experiments is not specified.

Freshness

Last updated 2025-10-14 21:31:29; freshness should be verified.

Geography

Spatial coverage is not specified in the provided metadata.